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Zishen Anning Recipe
- Development stage
- Unknown
- Lead developer
- Xiyuan Hospital
- Administration
- Oral
01
Overview
Zishen Anning Recipe is a Traditional Chinese Medicine (TCM) herbal formula developed by Xiyuan Hospital, China Academy of Chinese Medical Sciences, specifically for the treatment of insomnia in perimenopausal women. The formula is indicated for patients presenting with the TCM pattern of 'heart-kidney incompatibility' (also known as heart-kidney disharmony), which often manifests as sleep disturbances accompanied by anxiety and depression. As a complex herbal mixture, it is designed to restore physiological balance through holistic regulation rather than targeting a single biological pathway. It is administered orally, typically as a decoction or granules, and is currently undergoing clinical evaluation to establish its efficacy and safety in the perimenopausal population.
- Other names
- Zishen Anning DecoctionZishen Anning FormulaZishen Anning Fang滋肾安宁方
02
Targets
DRD (Dopamine receptors)ESR2 (ERβ)5-HT (Serotonin receptors)ESR1 (ERα)
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