Drug intelligence / Profile preview

Zishen Qinggan Formula

Development stage
Preclinical
Administration
Oral
01

Overview

Zishen Qinggan refers to a group of traditional Chinese medicine (TCM) formulas, typically composed of multiple herbs, used to treat a variety of conditions. These formulas are often investigated for their effects on hypertension, metabolic disorders, partial precocious puberty, benign prostatic hyperplasia, and autoimmune conditions like Sjögren's disease. Their therapeutic actions are generally attributed to modulating inflammatory responses, reducing oxidative stress, and influencing various biological pathways and protein expressions.

Other names
Qinggan Zishen FormulaZishen Qinggan GranulesYiqi Huayu Pinggan Zishen recipeQing Gan Zi Shen DecoctionBushen Qinggan FormulaZishen PillQihuang Jianpi ZiShen GranuleQingxin Zishen Decoction
02

Targets

FGF2BAX (Apoptosis regulator BAX)CASP3 (Caspase-3)CCL5 (C-C Motif Chemokine Ligand 5)IL-6 (Interleukin 6)JUN (Transcription factor Jun)MMP9 (Matrix metalloproteinase-9)CCL2 (C-C motif chemokine 2)NFE2L2 (Nuclear factor (erythroid-derived 2)-like 2)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)STAT3 (Signal Transducer and Activator of Transcription 3)TGFB1 (Transforming growth factor Beta-1 proprotein)TNFA (Tumor necrosis factor alpha (soluble))VEGFA (Vascular endothelial growth factor A)

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