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Zishen Qinggan Formula
- Development stage
- Preclinical
- Administration
- Oral
01
Overview
Zishen Qinggan refers to a group of traditional Chinese medicine (TCM) formulas, typically composed of multiple herbs, used to treat a variety of conditions. These formulas are often investigated for their effects on hypertension, metabolic disorders, partial precocious puberty, benign prostatic hyperplasia, and autoimmune conditions like Sjögren's disease. Their therapeutic actions are generally attributed to modulating inflammatory responses, reducing oxidative stress, and influencing various biological pathways and protein expressions.
- Other names
- Qinggan Zishen FormulaZishen Qinggan GranulesYiqi Huayu Pinggan Zishen recipeQing Gan Zi Shen DecoctionBushen Qinggan FormulaZishen PillQihuang Jianpi ZiShen GranuleQingxin Zishen Decoction
02
Targets
CCL2 (C-C motif chemokine 2)BAX (Apoptosis regulator BAX)IL-6 (Interleukin 6)TNFA (Tumor necrosis factor alpha (soluble))NFE2L2 (Nuclear factor (erythroid-derived 2)-like 2)MMP9 (Matrix metalloproteinase-9)FGF2CASP3 (Caspase-3)STAT3 (Signal Transducer and Activator of Transcription 3)JUN (Transcription factor Jun)CCL5 (C-C Motif Chemokine Ligand 5)VEGFA (Vascular endothelial growth factor A)TGFB1 (Transforming growth factor Beta-1 proprotein)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
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