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Zishui Bugan Decoction

Development stage: Preclinical
Administration: Oral

Overview

Zishui Bugan Decoction is a traditional Chinese medicine (TCM) herbal formula. It is not a single pharmaceutical compound but rather a multi-herb decoction, typically used in TCM practice for nourishing yin and tonifying the liver, often prescribed for symptoms associated with liver and kidney yin deficiency such as dizziness, insomnia, dry eyes, or tinnitus. The exact composition of herbs can vary by practitioner or region but commonly includes ingredients like Rehmannia glutinosa (Shu Di Huang), Cornus officinalis (Shan Zhu Yu), Dioscorea opposita (Shan Yao), Poria cocos (Fu Ling), Alisma orientale (Ze Xie), Paeonia suffruticosa (Mu Dan Pi), among others. Its mechanism of action is based on TCM theory—restoring balance to the body’s yin and yang—rather than on modern pharmacological targets. There are no well-established clinical trials or mechanistic studies in Western medicine literature specifically for this decoction.

Other names: Zishui Bugan Tang

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