Drug intelligence / Profile preview

zixue san

Development stage
Unknown
Lead developer
Tianjin Pharmaceutical Da Ren Tang Group
Administration
Oral
01

Overview

Zixue San is a traditional Chinese medicine (TCM) formula produced by Tianjin Hong Ren Tang Pharmaceutical, categorized as a heat-clearing and wind-extinguishing medication. It is historically recognized as one of the "Three Treasures of Cooling" (凉开三宝) in TCM, used to treat critical conditions involving high fever and neurological impairment. The formula is indicated for high fever, convulsions, delirium, and loss of consciousness, often associated with severe infections or "heat entering the pericardium" in TCM theory. It works by clearing internal heat, detoxifying the body, and calming the spirit. The preparation is typically a reddish-brown to grayish-brown powder with a fragrant odor and a cool, slightly bitter taste. Modern formulations are standardized to ensure safety and efficacy while often substituting endangered animal components with sustainable alternatives.

Brand names
Zixue San
Other names
紫雪散Zixue PowderPurple Snow Powder
02

Targets

STAT3 (Signal Transducer and Activator of Transcription 3)MMP9 (Matrix metalloproteinase-9)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)IL-6 (Interleukin 6)

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