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Ziyin Bone Clearing Pills (Ziyin Qinggu Wan) is a Traditional Chinese Medicine (TCM) formulation developed by the Gansu Provincial Hospital of Traditional Chinese Medicine. It is primarily indicated for the treatment of spinal tuberculosis, specifically targeting the "Yin deficiency and internal heat" (Yin xu nei re) pattern. The drug is typically administered as an adjunct to standard surgical intervention and the HRZE (isoniazid, rifampicin, pyrazinamide, and ethambutol) anti-tuberculosis chemotherapy regimen. Clinical evaluation focuses on its ability to improve clinical symptoms, regulate metabolomic profiles, and enhance the overall therapeutic outcome in adult patients. As a TCM product, it consists of multiple botanical and potentially animal-derived ingredients intended to nourish Yin, clear heat, and support bone health.
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