Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Ziyinliangxue
- Development stage
- Unknown
- Lead developer
- Shanghai Municipal Hospital of Traditional Chinese Medicine
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Ziyinliangxue is a Traditional Chinese Medicine (TCM) formula developed by the Shanghai Traditional Chinese Medicine Hospital, specifically indicated for the treatment of chronic glomerulonephritis (CGN). The formula is designed based on the TCM principle of nourishing Yin and cooling the blood (Ziyin Liangxue) to address the syndrome of Yin deficiency and internal heat often observed in renal patients. It typically consists of a combination of herbal ingredients such as Rehmannia glutinosa and Scrophularia ningpoensis. Clinically, it is used to reduce proteinuria and hematuria, modulate the immune response, and slow the progression of renal fibrosis. Research into its mechanism suggests it acts by inhibiting inflammatory pathways, regulating the Th17/Treg cell balance, and downregulating pro-fibrotic factors like TGF-beta1.
- Other names
- Ziyin Liangxue decoctionZiyin Liangxue formulaZiyin Liangxue granules滋阴凉血方
02
Targets
TNFA (Tumor necrosis factor alpha (soluble))TGFB1 (Transforming growth factor Beta-1 proprotein)IL-6 (Interleukin 6)
Beyond the preview
Go deeper on Ziyinliangxue.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Ziyinliangxue.