Drug intelligence / Profile preview

ZK-805623

Development stage
Preclinical
Lead developer
Bayer HealthCare Pharmaceuticals
Modality
Small Molecules
01

Overview

ZK-805623 is an experimental small molecule compound classified as a diarylether derivative. It was developed by Bayer HealthCare Pharmaceuticals as a potent, selective inhibitor of factor Xa, a key serine protease in the coagulation cascade. By inhibiting factor Xa, ZK-805623 was investigated for its potential antithrombotic effects and possible use in the prevention or treatment of thrombosis and related cardiovascular diseases. The compound is structurally related to other diphenoxypyridine derivatives and has been studied in preclinical settings but did not advance to clinical development[1][2][3]. No approved indications or marketed formulations exist for this drug.

02

Targets

F10 (Factor Xa)

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