Drug intelligence / Profile preview

ZLD-2

Development stage
Unknown
Lead developer
Sichuan University
01

Overview

ZLD-2: sourced facts only. name: "ZLD-2, the most promising compound, exhibited potent inhibitory activity against EZH2 and BRD4." [PMID:36774555]; target: "ZLD-2, the most promising compound, exhibited potent inhibitory activity against EZH2 and BRD4." [PMID:36774555]; target: "ZLD-2, the most promising compound, exhibited potent inhibitory activity against EZH2 and BRD4." [PMID:36774555]; developer: "Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610000, China." [PMID:36774555]; stage: "In vivo, ZLD-2 exhibited antitumor activity in a BxPC-3 mouse xenograft model, whereas GSK126 promoted tumor growth." [PMID:36774555]

02

Targets

BRD4 (Bromodomain-containing protein 4)EZH2 (Histone-lysine N-methyltransferase EZH2)

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