Drug intelligence / Profile preview

ZM-012

Development stage
Preclinical
Lead developer
Zomedica
Modality
Small Molecules
01

Overview

ZM-012 is a novel formulation of metronidazole, an anti-infective therapeutic developed by Zomedica Pharmaceuticals for veterinary use, specifically targeting acute diarrhea in dogs. Metronidazole is a nitroimidazole class prodrug that inhibits nucleic acid synthesis by forming nitroso radicals, which disrupt the DNA of microbial cells, leading to cell death in susceptible anaerobic bacteria and protozoa.

Brand names
EradiaAyradia
Other names
metronidazole oral suspension
02

Targets

DNA

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