Drug intelligence / Profile preview

Zoderm

Development stage
Unknown
Lead developer
Sandoz
Modality
Small Molecules
Administration
Topical
01

Overview

Zoderm is a brand name associated with two distinct topical dermatological products. One formulation is **ZoDerm 5.75% Benzoyl Peroxide Hydrating Wash**, a small molecule antibacterial treatment indicated for acne vulgaris. It works by releasing free-radical oxygen, which oxidizes bacterial proteins in *Cutibacterium acnes* (formerly *Propionibacterium acnes*) and provides keratolytic effects. This version was developed for DERM/arts, a division of Doak Dermatologics (a subsidiary of Bradley Pharmaceuticals). The second product is **Zoderm Cream or Lotion**, which contains the active ingredient **oxiconazole**, an imidazole antifungal. Oxiconazole inhibits the synthesis of ergosterol, a vital component of fungal cell membranes, by inhibiting the enzyme lanosterol 14-alpha-demethylase. This formulation is used to treat superficial fungal infections such as tinea pedis (athlete's foot), tinea cruris (jock itch), and tinea corporis (ringworm).

Brand names
Zoderm
02

Targets

CYP51A1 (Sterol 14α-demethylase)

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