Drug intelligence / Profile preview

Zoledronat OSTEO Labatec

Development stage
Unknown
Lead developer
Labatec Pharma
Modality
Small Molecules
Administration
Intravenous
01

Overview

Zoledronat OSTEO Labatec is an intravenous bisphosphonate containing zoledronic acid, developed and marketed by Labatec Pharma. It is formulated as a 5 mg/100ml solution for infusion. The drug is primarily indicated for the treatment of osteoporosis in postmenopausal women and men, the prevention of clinical fractures after hip fracture, and the treatment of Paget's disease of bone. Zoledronic acid acts by inhibiting osteoclast-mediated bone resorption through the inhibition of farnesyl pyrophosphate synthase (FPPS) in the mevalonate pathway, which leads to increased bone mineral density and reduced bone turnover. It is typically administered as a single 5 mg intravenous infusion once a year for the treatment of osteoporosis.

Brand names
Zoledronat OSTEO LabatecZoledronat OSTEO
Other names
zoledronic acidzoledronate
02

Targets

GGPPS1 (Geranylgeranyl pyrophosphate synthase)FDPS (Farnesyl pyrophosphate synthase)

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