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ZP10068 is an investigational, selective, and long-acting inhibitor of Complement C3 developed by Zealand Pharma. It is a synthetic peptide therapeutic designed to target the complement pathway and inhibit the central component C3 protein of the complement cascade. The drug aims to treat a range of complement-mediated diseases associated with chronic inflammation, including rare immune-mediated disorders such as paroxysmal nocturnal hemoglobinuria, cold agglutinin disease, myasthenia gravis, and C3 glomerulopathy. As of May 2024, ZP10068 has completed preclinical activities with plans for first-in-human clinical trials[1][2][3].
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