Zp17

Zp17: sourced facts only. name: "Zp17 illustrated superior STING degradation activity and exhibited significantly lower cytotoxicity compared to SP23 in vitro." [PMID:42372458]; target: "Zp17 illustrated superior STING degradation activity and exhibited significantly lower cytotoxicity compared to SP23 in vitro." [PMID:42372458]; developer: "Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan Key Laboratory of Organic Functional Molecule and Drug Innovation, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, PR China." [PMID:42372458]; modality: "Collectively, compound Zp17 warrants further investigation as PROTAC degrader of STING." [PMID:42372458]; stage: "In mouse acute kidney injury (AKI) model, Zp17 effectively alleviated renal function impairment induced by cisplatin." [PMID:42372458]