Drug intelligence / Profile preview

ZP5-9676

Development stage
Phase 3
Lead developer
Zero Point Five Therapeutics
Modality
Small Molecules
Administration
Oral
01

Overview

ZP5-9676 is a small molecule anthelmintic drug candidate developed by Zero Point Five Therapeutics for the treatment of soil-transmitted helminthiasis, including infections caused by *Ascaris* (roundworm), *Trichuris* (whipworm), *Necator americanus*, and *Ancylostoma duodenale* (hookworms). It is designed as a single-dose therapy with a child-friendly formulation that remains localized in the intestine to minimize systemic exposure and enhance safety, particularly for pediatric populations. The precise mechanism of action has not been disclosed. ZP5-9676 is currently in Phase 3 clinical trials for helminthiasis in both pediatric and adult patients.

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