Drug intelligence / Profile preview

ZQ-5

Development stage
Preclinical
Lead developer
Hubei University of Technology
01

Overview

ZQ-5: sourced facts only. name: "Compounds ZQ-4, ZQ-5, ZQ-6, and ZQ-7 inhibit MAGL activity in a time-dependent and concentration-dependent manner." [PMID:40107037]; target: "Compounds ZQ-4, ZQ-5, ZQ-6, and ZQ-7 inhibit MAGL activity in a time-dependent and concentration-dependent manner." [PMID:40107037]; developer: "Cooperative Innovation Center of Industrial Fermentation (Ministry of Education & Hubei Province), Hubei Key Laboratory of Industrial Microbiology, Wuhan 430068, China; Key Laboratory of Fermentation Engineering (Ministry of Education), Wuhan 430068, China, National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan 430068, China." [PMID:40107037]; stage: "Significantly increased 2-AG levels were detected in MDA-MB-231 cells treated with MAGL inhibitor ZQ-5, ZQ-6, ZQ-7, ZQ-19, and KML29, a previously identified MAGL covalent inhibitor." [PMID:40107037]

02

Targets

MGLL (Monoacylglycerol lipase)

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