Zushima plaster

Zushima plaster is a traditional Chinese medicinal patch containing extracts from Cortex Daphnes (Zushima). It contains bioactive compounds including daphnetin, coumarins, lignans, flavonoids, and diterpenes. The plaster is primarily used for treating inflammatory conditions such as knee osteoarthritis and rheumatoid arthritis through topical application. Its mechanism of action involves inhibition of prostaglandin E2 generation by suppressing cyclooxygenase-2 expression. Clinical studies have shown it provides effective pain relief and improves joint function when applied to affected areas for 24 hours daily.

Brand names

Zushima plaster

Other names

Cortex Daphnes patchZushima total coumarin Gelatum plaster