ZyCoV-D

ZyCoV-D is a DNA plasmid-based vaccine developed for the prevention of COVID-19. It was created by Cadila Healthcare (now known as Zydus Lifesciences) in India, with support from the Biotechnology Industry Research Assistance Council. The vaccine uses a non-replicating and non-integrating plasmid vector that carries the gene encoding the spike (S) protein of SARS-CoV-2. Once administered intradermally using a needle-free injector, host cells take up the plasmid and express the spike protein, which elicits both humoral and cellular immune responses against SARS-CoV-2. The vaccine is approved for emergency use in India for individuals 12 years of age and older[1][2][4][5]. Its DNA platform offers advantages such as improved stability, minimal biosafety requirements, and reduced cold chain needs.

Brand names

ZyCoV-D

Other names

ZYCOV-D