Drug intelligence / Profile preview

ZZ1001

Development stage
Preclinical
Lead developer
Zhongze Therapeutics
Modality
Small Molecules
01

Overview

ZZ1001 (also known as ZZ-1001) is a discovery-stage small molecule drug candidate being developed by Zhongze Therapeutics (Zhongze Therapeutics Hong Kong Ltd.) for the treatment of schizophrenia. It is designed to act as a multi-target modulator, specifically targeting serotonin (5-HT) receptors and dopamine D5 receptors. The compound is part of Zhongze's pipeline of innovative central nervous system (CNS) therapies, which includes other candidates like ZZ6398 (SIPI6398) and ZZ2101. ZZ1001 aims to address the complex pathophysiology of schizophrenia by modulating neurotransmitter pathways associated with the disease's positive, negative, and cognitive symptoms.

02

Targets

DRD5 (Dopamine D5 Receptor)5-HT (Serotonin receptors)

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