All examples

Which China-origin ADCs now in Phase 2 or 3 have licensing agreements with US partners since 2023?

Data pulled ·

4 assetsChina-origin programs → US partnersAgreements since 2023
Phase 3 3Phase 2 1Current global phase · China-origin includes overseas subsidiaries · Selected assets
EGFR / HER3 · ADCPhase 3

BL-B01D1

izalontamab brengitecan

LicensorSystImmuneBiokin parent · China
US partnerBristol Myers Squibb
Current developmentChina · TNBC, ESCC, NPC
AgreementDec 2023
Nectin-4 · ADCPhase 3

CRB-701

SYS6002

LicensorCSPC MegalithCSPC group · China
US partnerCorbus Pharmaceuticals
Current developmentChina · cervical cancer
AgreementFeb 2023
DLL3 · ADCPhase 2*

SHR-4849

IDE849

LicensorHengrui PharmaChina
US partnerIDEAYA Biosciences
Current developmentMonotherapy · Phase 1/2 program
AgreementDec 2024
TROP2 / HER3 · ADCPhase 3

JSKN016

TROP2 × HER3 ADC

LicensorJiangsu AlphamabChina
US partnerPathosAI
Current developmentTNBC
AgreementAug 2026

*IDE849: monotherapy is labelled Phase 2 within a Phase 1/2 study; combinations are Phase 1.

Phases & territories
AssetAnnouncedPhase at announcementCurrent phase · geographyRights
BL-B01D1 / izalontamab brengitecan2023-12-11Global Phase 1; China phase unspecifiedPhase 3 in China: TNBC, ESCC and nasopharyngeal carcinomaUS co-development/co-commercialization; BMS exclusive rest-of-world rights outside mainland China
CRB-701 / SYS6002Feb 2023 · license monthChina Phase 1 in 2023; signing-day phase unspecifiedChina: Phase 3 cervical; Phase 2 mUC. US/EU: Phase 2/3 pending.US, Canada, EU/EFTA, UK and Australia
SHR-4849 / IDE8492024-12-29Phase 1Monotherapy: Phase 2*; combinations: Phase 1Outside Greater China
JSKN0162026-08-03Phase 3 TNBC; earlier-phase studies also ongoingPhase 3 · TNBCOutside mainland China, Hong Kong, Macau and Taiwan

Dates show announcements or disclosed license months.

CLI query

Deal → drug → developer · China-based developer/seller filter

python3 -m gosset.cli deals \
  --deal-type Licensing \
  --since 2023-01-01 \
  --where drug.modality=ADC \
  --where drug.developer.country=China \
  --where drug.phase=2,3 \
  --where seller.country=China \
  --where 'buyer.country=United States' \
  --all --include-ids --debug

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