Target intelligence / Profile preview

24-Methylenecholesterol

Molecular classification
Sterol, Phytosterol, Lipid
01

Overview

24-Methylenecholesterol is a C28 sterol that serves as a critical intermediate in the biosynthetic pathways of various sterols across different kingdoms, including plants, fungi, and marine invertebrates. It is characterized by a double bond at the 24(28) position and is a precursor to ergosterol in certain organisms and brassinosteroids in plants (PubChem, CID 92105). In the context of entomology, it is a major sterol found in pollen and is essential for the growth and development of honeybees (Apis mellifera), who cannot synthesize sterols de novo (PubMed, PMID 22533134). While it plays a structural role in cell membranes and acts as a metabolic precursor, it is not a therapeutic target in the traditional sense of a protein receptor or enzyme. Research primarily focuses on its role in nutrition, chemical ecology, and its presence in marine sponges and algae as a chemotaxonomic marker (Wikipedia, 24-Methylenecholesterol).

Other names
Ergosta-5,24(28)-dien-3beta-olChalinasterolOstreasterol24-methylene-cholest-5-en-3-beta-ol
02

Biological functions

Membrane structural componentSterol biosynthesis intermediateNutritional component in insects
03

Disease associations

Other
04

Safety considerations

Limited data on human pharmacological effects
05

Biomarkers

Dietary phytosterol markerMarine organism chemotaxonomic marker

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