40S small subunit processome assembly factor 1 (FSAF1)

40S small subunit processome assembly factor 1 (FSAF1) is a protein involved in the biogenesis of the ribosomal small subunit in eukaryotes, acting as part of the small-subunit processome complex. It facilitates RNA binding and is important for proper assembly and processing of the nascent pre-rRNA, but is not characterized as a therapeutic target, receptor, enzyme, or transporter. Its major function is in ribosome production, rather than in modulating signaling pathways or serving as a druggable protein. FSAF1 is encoded by the C1orf131 gene and has no known direct links to current clinical biomarkers, drugs, or mechanisms of pharmacological action[1]. Key points supporting this assessment: - The canonical full name is "40S small subunit processome assembly factor 1"[1]. - The canonical abbreviation is "FSAF1"[1]. - It is not a classical drug target (such as a receptor, enzyme, transport protein, or known actionable disease protein)[1]. - Alternative designations in the literature and databases include C1orf131 and related synonyms, reflecting historic gene nomenclature[1]. - The protein's primary molecular function is in **ribosome assembly via RNA binding and ribosomal RNA processing**[1]. - No direct disease-modifying role, no known small-molecule drug interactions, and no defined mechanism of drug action reported; not reported as a biomarker or as associated with therapeutic safety issues[1]. Notes on incorrectness: - "FSAF1" and the associated full name are often confused with "FAF1" (Fas-associated factor 1), which is a death-promoting protein involved in apoptosis and a known candidate cancer target[5]. This query refers to a different, non-druggable, ribosome biogenesis factor, and not a therapeutic target. - No evidence was found for FSAF1 being a receptor, enzyme, or protein of drug development interest. If you are seeking information about Fas-associated factor 1 (FAF1), which is a distinct clinically relevant target linked to apoptosis, cancer, and drug modulation, clarify the abbreviation, as this is a separate entry with distinct biological functions and target utility[5].

Other names

C1orf131cPERP-ADKFZp547B1713uncharacterized protein C1orf131