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Target intelligence / Profile preview
5-hydroxytryptamine receptor 1D pseudogene 1 (HTR1DP1)
- Target
- HTR1DP1
- Molecular classification
- Other (Pseudogene)
01
Overview
5-hydroxytryptamine receptor 1D pseudogene 1 (HTR1DP1) is a human pseudogene related to the HTR1D gene, which encodes a G protein-coupled serotonin receptor. Unlike the functional HTR1D gene, HTR1DP1 does not encode an active protein. Pseudogenes like HTR1DP1 arise via gene duplication or retrotransposition and typically accumulate disabling mutations that prevent them from producing functional protein products. While some pseudogenes can exert regulatory effects at the RNA level (such as acting as miRNA decoys), there is no evidence for such a role specific to HTR1DP1. This pseudogene is not considered a drug target or involved in recognized therapeutic mechanisms[2].
- Other names
- HTR1DP1HTR1D pseudogene 1
02
Biological functions
No direct protein functionPseudogenes can sometimes act as regulatory RNAs (e.g., competing endogenous RNAs) but there is no specific evidence for functional roles of HTR1DP1[2]
03
Disease associations
No direct disease associationSome pseudogenes in general may have regulatory roles in cancer or other diseases, but no such function is established for this one[2]
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