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Target intelligence / Profile preview
50S Ribosomal Protein L32 (L32)
- Target
- L32
- Molecular classification
- Ribosomal Protein
01
Overview
50S ribosomal protein L32 is a structural component of the large (50S) subunit of prokaryotic ribosomes. It is essential for ribosome assembly, stability, and translation. It interacts with rRNA and other ribosomal proteins. The eukaryotic homolog, RPL32, has been implicated in cancer.
- Other names
- RpmF50S ribosomal subunit protein L32RPL32 (eukaryotic homolog)
02
Mechanism of action
Inhibition of bacterial protein synthesis by disrupting ribosome function.
03
Biological functions
Structural constituent of ribosomerRNA bindingTranslation
04
Disease associations
Cancer (in eukaryotes - RPL32)
05
Safety considerations
Inhibition of essential ribosomal function can lead to broad toxicity.Potential for off-target effects on eukaryotic ribosomes (though prokaryotic and eukaryotic ribosomes differ)
06
Interacting drugs
Troleandomycin
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