5S ribosomal RNA 4 (5S rRNA 4)

5S ribosomal RNA is a highly conserved, ~120-nucleotide RNA that forms a critical part of the eukaryotic (and prokaryotic) large ribosomal subunit (60S in eukaryotes)[1][2]. It serves a structural and organizational role in the assembly and function of the ribosome, bridging ribosomal proteins and other rRNA to guide ribosomal biogenesis and ensure efficient protein synthesis[1][2][3]. The term "5S ribosomal RNA 4" likely refers to one member of a set of tandemly repeated 5S rRNA genes (with “4” indicating a specific copy or locus), which are common in higher eukaryotic genomes[1][2]. 5S rRNA is not a therapeutic target (such as a receptor, enzyme, or transporter), nor is it commonly associated as a direct biomarker or drug target, but its essential function means genetic or biogenetic disruptions can have profound effects on cell growth and protein production[1][2].

Other names

RNA5S45S rRNA 4RN5S4

Not applicable (RNAs of this class themselves are not targets of therapeutic agents; their disruption by antibiotics such as in bacteria may involve interaction with associated ribosomal proteins or RNA regions)