5S ribosomal RNA 9 (5S rRNA 9)

5S ribosomal RNA 9 is one of several nearly identical gene copies encoding the 5S ribosomal RNA (5S rRNA), a small, highly conserved RNA molecule (~120 nucleotides) that is an essential structural and functional component of the large ribosomal subunit in all domains of life, except for mitochondrial ribosomes in fungi and animals[2][1][3]. 5S rRNA is crucial in coordinating the assembly and structural integrity of the ribosome by connecting core functional centers, including the peptidyl transferase and GTPase-associated centers, and acts as a physical transducer of information between these regions during protein synthesis[1][2]. While critical for cell function, multiple copies of the 5S rRNA gene exist, and these are not distinct therapeutic targets but are rather fundamental, non-coding components required for ribosome and cell viability[2][3].

Other names

5S rRNA 9RN5S9RNA5S9

Not applicable (no drugs directly target 5S rRNA for therapeutic purposes)