5S ribosomal RNA pseudogene 109 (RNA5SP109)

5S ribosomal RNA pseudogene 109 (RNA5SP109) is a non-protein-coding DNA sequence in the human genome that resembles the functional 5S ribosomal RNA gene, but has lost its ability to encode a functional ribosomal RNA due to mutations or truncations; such sequences are known as pseudogenes. 5S rRNA gene clusters are often subject to retrotransposition or DNA duplication, generating many non-functional processed pseudogenes (like RNA5SP109) dispersed throughout the genome. These pseudogenes do not contribute structurally or functionally to ribosomes and do not serve a known biological or pathological function. Although some pseudogenes in other contexts have been found to generate non-coding RNAs with regulatory potential, this is not known or documented for RNA5SP109. Summary of Key Facts: - Not a functional receptor, enzyme, transporter, or drug target; no evidence it encodes an active RNA. - Classified as a processed noncoding pseudogene of the highly conserved 5S rRNA, a true ribosomal RNA component. - No known disease associations, biomarker roles, or drug interactions. - Not relevant to therapeutic targeting or drug discovery applications; its identification in bioinformatic pipelines is common but carries no direct implication for cell function. For additional context: functional 5S ribosomal RNA is an essential structural and regulatory component of the large subunit of the ribosome, playing roles in ribosome assembly and possibly allosteric signal transmission. Pseudogenes like RNA5SP109 are legacy genomic elements and are not transcribed into functional rRNA.

Other names

RN5S109RNA5SP109RNA, 5S ribosomal 109