Target intelligence / Profile preview

5S ribosomal RNA pseudogene 125 (RNA5SP125)

Target
RNA5SP125
Molecular classification
Other (Pseudogene, non-coding RNA)
01

Overview

5S ribosomal RNA pseudogene 125 (RNA5SP125) is a member of the pseudogene family, derived from the canonical 5S ribosomal RNA, a structural RNA component of the large subunit of the ribosome involved in protein synthesis[1][3]. As a pseudogene, RNA5SP125 does not encode a functional product and is not directly involved in canonical ribosomal function. Pseudogenes can, however, sometimes be transcribed; in some cases, pseudogene expression has been implicated in regulatory roles or as disease biomarkers, especially in cancer, through mechanisms such as acting as long non-coding RNAs (lncRNAs) or competing endogenous RNAs (ceRNAs)[2]. There is no evidence suggesting RNA5SP125 functions as an actionable drug target, receptor, enzyme, or other typical therapeutic target class.

Other names
RN5S125RNA, 5S ribosomal 125RNA5SP125
02

Disease associations

Other (Possible biomarker or regulatory role in cancer as pseudogene)
03

Biomarkers

Possible role as a biomarker depending on its expression profile in cancer, like other expressed pseudogenes[2]

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