5S ribosomal RNA pseudogene 128 (RNA5SP128)

5S ribosomal RNA pseudogene 128 (RNA5SP128) is a processed pseudogene in the human genome, corresponding to a nonfunctional duplicate of the 5S ribosomal RNA gene[2]. Like other pseudogenes, it cannot produce functional 5S rRNA due to disabling mutations or sequence changes. 5S rRNA itself is a short RNA component (~120 nucleotides) of the large ribosomal subunit, critical for ribosome structure and function in active genes[1][3]. Pseudogenes such as RNA5SP128 are typically considered "genomic fossils," but some are transcriptionally active and may have regulatory functions at the RNA level, such as acting as antisense transcripts or miRNA sponges, though specific evidence for RNA5SP128 is not documented[2]. RNA5SP128 is not a protein, not a therapeutic target (it is neither a receptor, enzyme, transporter, nor druggable molecule), and does not have known drug interactions. RNA5SP128 (5S ribosomal RNA pseudogene 128) is an unprocessed or processed pseudogene of the 5S ribosomal RNA gene, not a therapeutic target, with no known function, drug interactions, or clinical relevance as a biomarker or safety concern[1][2][3].

Other names

RN5S128RNA, 5S ribosomal 1285S ribosomal RNA pseudogene 128RNA5SP128