5S ribosomal RNA pseudogene 137 (RNA5SP137)

5S ribosomal RNA pseudogene 137 (RNA5SP137) is a processed pseudogene derived from the 5S ribosomal RNA gene family in the human genome. Unlike functional 5S rRNA genes, which are essential components of the ribosome and play a critical role in ribosomal assembly and protein synthesis[1][3], RNA5SP137 contains mutations that render it non-functional and it does not encode an active RNA or protein product[2][6]. Pseudogenes like RNA5SP137 arise through duplication or retrotransposition events but lose their ability to function due to mutations or lack of required regulatory elements[6]. There is no evidence that this pseudogene serves as a therapeutic target, nor is it associated with disease biomarkers, drug interactions, or known safety issues. Its presence in the genome reflects the evolutionary history of the ribosomal RNA gene family rather than an active biological or disease-related role[6].

Other names

RN5S137RNA5SP137RNA, 5S ribosomal pseudogene 137RNA, 5S ribosomal 137

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