5S ribosomal RNA pseudogene 164 (RNA5SP164)

5S ribosomal RNA pseudogene 164 (RNA5SP164) is a processed pseudogene, meaning it arose by retrotransposition of an RNA intermediate from the functional 5S rRNA gene[4][5]. As with other pseudogenes, RNA5SP164 does not encode a functional product and does not participate in ribosome biogenesis or other biological processes[2][5]. The functional 5S rRNA is a highly conserved component of the large ribosomal subunit required for protein synthesis in all cells[1][3]. Pseudogenes of 5S rRNA exist in multiple copies throughout the eukaryotic genome, often as processed or unprocessed pseudogenes, but these are considered "genomic fossils" without coding function[1][4]. While the global expression of certain pseudogenes can vary in disease (notably cancer), there is no evidence that RNA5SP164 has a validated functional impact or acts as a drug target or biomarker[6]. Key points: - RNA5SP164 is not a protein, enzyme, receptor, or other canonical therapeutic target. - Classified as a pseudogene, it is non-functional and is not associated with drug action, biomarker status, or direct disease mechanisms[2][4][5]. - Its name and locus derive from sequence similarity to the 5S ribosomal RNA gene.

Other names

RN5S164RNA, 5S ribosomal 164RNA5SP164