Target intelligence / Profile preview

5S ribosomal RNA pseudogene 178 (RNA5SP178)

Target
RNA5SP178
Molecular classification
Pseudogene, Non-coding RNA pseudogene, rRNA pseudogene
01

Overview

5S ribosomal RNA pseudogenes are genomic sequences similar to the 5S rRNA gene, but lacking functional activity due to mutations, truncations, or lack of regulatory elements required for transcription or translation. RNA5SP178 is one of many processed pseudogenes corresponding to the canonical 5S rRNA gene in the human genome. While canonical 5S rRNA is an essential structural component of the ribosome and involved in protein synthesis, pseudogenes are typically nonfunctional remnants that may rarely acquire regulatory capacity (for example, acting as ceRNAs) in specific disease contexts, but this is uncommon and not established for RNA5SP178. No drugs, therapeutic mechanisms, or biomarker roles are associated with RNA5SP178. In summary, RNA5SP178 is not a functional gene, receptor, enzyme, nor a recognized target in therapeutic development. Its classification is a pseudogene, reflecting an inactive, non-coding RNA sequence related to 5S rRNA, with no established biological or clinical relevance.

Other names
RN5S178RNA5SP178RNA, 5S ribosomal 1785S ribosomal RNA pseudogene 178
02

Mechanism of action

Not applicable; no mechanism of action involving drugs is known.

03

Biological functions

No direct biological function; pseudogenes may sometimes exert regulatory roles, e.g. as competing endogenous RNAs (ceRNAs) by sponging microRNAs or regulating parent gene expression, but this requires specific supporting evidence and is not established for RNA5SP178
04

Disease associations

OtherNo established disease association; some pseudogene transcripts have been associated with immune regulation, but there is no data specific to RNA5SP178

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