5S ribosomal RNA pseudogene 187 (RNA5SP187)

5S ribosomal RNA pseudogene 187 (RNA5SP187) is a member of the human rRNA pseudogene family that shares sequence similarity to functional 5S ribosomal RNA genes, but does not produce functional ribosomal RNA due to its pseudogene status. Pseudogenes like RNA5SP187 are genomic elements derived from once-functional genes that have lost their coding capability as a result of accumulated mutations, such as frameshifts, stop codons, or insertions into transcriptionally inactive regions[4][2]. Most rRNA pseudogenes, including RNA5SP187, are non-coding and not transcribed, and they do not participate in ribosome assembly or protein synthesis. There is no current evidence that RNA5SP187 has a role as a therapeutic target, biomarker, or molecular drug target, and its biological relevance is tied only to pseudogene biology rather than any direct functional or disease-related activity[4]. Note: - This entry is best considered *incorrect* as a conventional therapeutic target, since it is a pseudogene, not an active receptor, enzyme, or regulatory molecule[2][4]. - Pseudogenes can sometimes play regulatory roles (for example, as long non-coding RNAs or ceRNAs in competitive endogenous RNA networks), but there is no evidence that RNA5SP187 has any such function at present[4]. - For structured data, this entity should be flagged as a pseudogene and not as a validated therapeutic target.

Other names

RN5S187RNA, 5S ribosomal 187RNA5SP187

Not applicable (no validated function or drug interaction)