5S ribosomal RNA pseudogene 213 (RNA5SP213)

5S ribosomal RNA pseudogene 213 is a genomic DNA sequence that closely resembles the 5S ribosomal RNA gene but is non-functional due to accumulated mutations. Pseudogenes like RNA5SP213 typically result from gene duplication or retrotransposition events and do not yield functional RNAs or proteins. They are generally considered "genomic fossils," though in some rare instances, pseudogenes can regulate gene networks, alter transcript dynamics, or serve as microRNA decoys. However, there is no evidence that RNA5SP213 itself has such activity[2][4].\n\nSummary of significance and context:\n- 5S rRNA is an essential structural RNA component of the ribosome in most organisms, involved in stabilizing the ribosome and mediating interactions with ribosomal proteins[1][3].\n- A pseudogene like RNA5SP213 does not produce functional rRNA and is not involved in ribosome assembly or function[2][4].\n- There are many ribosomal RNA pseudogenes in the human genome with no known function; some pseudogenes have gained regulatory roles, but there is no information supporting such a role for RNA5SP213.\n\nIf you are seeking therapeutic targets, genes classified as pseudogenes—especially ribosomal RNA pseudogenes like RNA5SP213—are generally not considered druggable or actionable for biomedical research or therapy[2][4].

Other names

RN5S213RNA5SP213RNA, 5S ribosomal 213