5S ribosomal RNA pseudogene 245 (RNA5SP245)

RNA, 5S ribosomal pseudogene 245 (RNA5SP245) refers to a processed pseudogene in the human genome derived from the 5S ribosomal RNA gene[2]. Pseudogenes are non-functional sequences that resemble functional genes but carry disabling mutations or lack regulatory elements, typically arising from duplication or retrotransposition events[2][3]. The canonical 5S ribosomal RNA is a 120-nucleotide molecule that forms part of the large ribosomal subunit and is critical for ribosome structure and function in translation[1][3]; however, RNA5SP245 does not produce a functional RNA and does not contribute to ribosome assembly or protein synthesis. Most 5S rRNA pseudogenes do not produce detectable transcripts, have limited or no biological activity, and are not currently implicated in human disease or targeted by any therapeutic agents[2][4]. If canonical functional 5S ribosomal RNA information is required, refer to "5S ribosomal RNA," which is a component of ribosomes involved in protein synthesis and has clear biological and structural roles[1][3]. RNA5SP245 should be considered a sequence artifact, not a molecular target.

Other names

RN5S245RNA, 5S ribosomal 245RNA5SP245