5S ribosomal RNA pseudogene 303 (RNA5SP303)

RNA5SP303 (5S ribosomal RNA pseudogene 303) is a human pseudogene belonging to the large family of 5S ribosomal RNA pseudogenes. Unlike functional 5S ribosomal RNA genes, it has accumulated mutations preventing it from being transcribed into a functional ribosomal RNA molecule or participating in ribosome assembly. 5S rRNA pseudogenes like RNA5SP303 arise mainly via retrotransposition or gene duplication followed by loss of function[2][4]. While pseudogenes in general can sometimes have regulatory impacts—such as influencing gene expression via antisense transcripts, endogenous siRNAs, miRNA sponging, or functioning as long noncoding RNAs[4][6]—there is no specific evidence that RNA5SP303 has a defined biological function or disease association. It is not considered a therapeutic target, and no interacting drugs, biomarker roles, or safety concerns are described. **Notes:** - This entry is **not a therapeutic target** in the traditional sense of a drug, antibody, or biologic aiming to modulate activity for disease therapy[2][4]. - The entity is a **pseudogene**, not a coding gene, functional RNA, receptor, enzyme, transporter, or transcription factor. - No known mechanism of action, biomarker use, or disease linkage specific to RNA5SP303 is described in the literature. Some 5S rRNA pseudogenes may contribute to broad genomic regulatory mechanisms but these are general and not specific to RNA5SP303[2][4][6]. - A pseudogene designation means **"not a target"** under standard drug discovery definitions. - The name is **correct**, but **not a target** by canonical criteria and thus the "is_incorrect" flag is set to **true** to denote inappropriate categorization as a drug/metabolic target.

Other names

RN5S303RNA5S ribosomal 303RNA5SP303