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5S ribosomal RNA pseudogene 365 (RNA5SP365) is a processed pseudogene related to the canonical 5S ribosomal RNA (5S rRNA) gene. 5S rRNA itself is a ~120-nucleotide non-coding RNA acting as a structural component of the large ribosomal subunit, critical for ribosome function and assembly. However, pseudogenes such as RNA5SP365 arise by retrotransposition events, resulting in non-functional gene copies randomly integrated into the genome, often lacking regulatory elements and the ability to be transcribed. These 5S rRNA pseudogenes are generally considered genomic fossils without functional roles in protein synthesis or known impact on disease or therapy. This entry is not a therapeutic target; it is not a receptor, enzyme, transporter, or any known drug target. RNA5SP365 is a pseudogene—by definition, an inactive copy of a gene that no longer produces functional RNA or protein. There are hundreds of 5S rRNA pseudogene annotations in the human genome; none are generally cataloged as functionally relevant or therapeutically targeted. No drugs, biomarkers, or disease associations are reported for this specific pseudogene. The target is incorrect if queried as a therapeutic target or biologically relevant molecule. The name is accurate as a pseudogene annotation, but it should not be used as a model receptor, enzyme, or therapeutic target.
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