5S ribosomal RNA pseudogene 39 (RNA5SP39)

5S ribosomal RNA pseudogene 39 (RNA5SP39) is a processed pseudogene related to the 5S ribosomal RNA gene. It does not produce a functional ribosomal RNA product and is classified as a non-coding RNA pseudogene.[2][3] Pseudogenes, including rRNA pseudogenes like RNA5SP39, generally arise from ancestral ribosomal RNA genes through processes such as retrotransposition or sequence duplication followed by inactivation due to mutation.[1][3] Most pseudogenes are transcriptionally inactive, but some can be expressed and may have regulatory functions in gene expression via RNA interference mechanisms or by acting as competitive endogenous RNAs; however, these roles are not universally established and no specific functional data is available for RNA5SP39 itself.[1][4][5] rRNA pseudogenes are a large and diverse family, typically bearing sequence similarity to their functional parental rRNA genes but lacking protein-coding potential and canonical rRNA roles.[8] There is no evidence that RNA5SP39 acts as a disease gene, therapeutic target, or direct clinical biomarker.

Other names

RN5S39RNA, 5S ribosomal 39RNA5SP39[2]