5S ribosomal RNA pseudogene 396 (RNA5SP396)

RNA, 5S ribosomal pseudogene 396 (RNA5SP396) is a human pseudogene derived from the 5S ribosomal RNA gene family and is not a functional protein-coding gene or an established therapeutic target[2][5][6]. It is classified as a processed pseudogene—formed by retrotransposition and lacking full biological functionality[4][5][6].\n5S ribosomal RNA pseudogene 396 (abbreviated RNA5SP396 or RN5S396) is a processed ribosomal RNA pseudogene, meaning it originated from the 5S ribosomal RNA gene via retrotransposition, lacks introns, and does not encode a functional ribosomal RNA[5][6][4]. Unlike the functional 5S rRNA gene, which is an essential structural and functional component of the large ribosomal subunit in all domains of life[1][3], this pseudogene does not contribute to ribosome structure or function. Pseudogenes such as RNA5SP396 may rarely be transcribed, but generally lack biological activity and are not considered drug targets or biomarkers. There are no known disease associations or therapeutic applications for this particular pseudogene[4][5].\nThis gene serves primarily as a non-functional genomic element in the human genome. Its identification is significant for genome annotation and understanding rRNA gene evolution but not for therapeutic targeting or clinical practice[5][6].

Other names

RN5S396RNA, 5S ribosomal pseudogene 396RNA, 5S ribosomal 396RNA5SP396