5S ribosomal RNA pseudogene 410 (RNA5SP410)

RNA, 5S ribosomal pseudogene 410 is a predicted non-coding RNA gene classified as a pseudogene of 5S ribosomal RNA. Pseudogenes like RNA5SP410 are considered to be remnants of functional genes that have accumulated mutations preventing their normal expression or function—they are not transcribed or translated to produce a functional RNA or protein product in the cell. The canonical 5S ribosomal RNA (5S rRNA) sequence is a structural and functional component of cytoplasmic ribosomes involved in protein synthesis. However, pseudogenes such as RNA5SP410 arise by gene duplication or retrotransposition events but have lost their principal biological function. While some rRNA pseudogenes may be transcribed, and in extremely rare cases exert secondary regulatory or "decoy" functions in ceRNA networks, such activities are not demonstrated for RNA5SP410 or for most rRNA pseudogenes. RNA5SP410 is not considered a therapeutic target or a physiologically relevant receptor, enzyme, or signaling protein.\n\nThe inclusion of this gene as a "target" is generally incorrect: it is not a druggable target, nor does it have a recognized biological, pharmacological, or disease role. The gene is listed in genome annotations as a pseudogene, which means it has no known function and is not expressed as a functional product in normal biology. If the intent was to identify a therapeutic or signaling target, then this entry is not appropriate.

Other names

RNA5SP410RN5S410RNA, 5S ribosomal 410