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Target intelligence / Profile preview
5S ribosomal RNA pseudogene 438 (RNA5SP438)
- Target
- RNA5SP438
- Molecular classification
- Pseudogene, Non-coding RNA (specifically, a 5S ribosomal RNA-derived sequence)
01
Overview
5S ribosomal RNA pseudogene 438 (RNA5SP438) is a non-functional, non-coding RNA gene derived from the 5S ribosomal RNA gene. It belongs to the family of processed or unprocessed pseudogenes present in the human genome. While functional 5S rRNA is an essential structural and regulatory component of the large ribosomal subunit[1][3], RNA5SP438 contains sequence alterations that render it incapable of producing a functional RNA product and it does not participate in ribosome biogenesis or protein synthesis[5]. Pseudogenes such as RNA5SP438 may be transcribed, and the expression patterns of pseudogenes have gained recent interest as possible regulatory RNAs or prognostic markers in cancer[4][6]; however, there is currently no specific functional role or druggability attributed to RNA5SP438.
- Other names
- RN5S438RNA, 5S ribosomal pseudogene 438RNA5SP438RNA, 5S ribosomal 438
02
Biological functions
Other (Pseudogenes generally do not encode functional products; some pseudogenes can regulate gene expression at the RNA level, but there is no specific evidence for this function with RNA5SP438)
03
Disease associations
Other (Pseudogenes in general may show altered expression in cancers or other diseases and may be used as molecular markers, but there is no disease association specific to RNA5SP438 as of current knowledge)
04
Biomarkers
Other (Pseudogene expression signatures, including 5S rRNA pseudogenes, are being investigated as prognostic and molecular subtype biomarkers in cancer, but not specifically for RNA5SP438)
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