5S ribosomal RNA pseudogene 464 (RNA5SP464)

5S ribosomal RNA pseudogene 464 (RNA5SP464) is a pseudogene homologous to the 5S ribosomal RNA gene. 5S ribosomal RNA itself is a 120-nucleotide structural RNA integral to the large ribosomal subunit in most eukaryotes and prokaryotes, playing a key role in ribosome biogenesis and protein synthesis[1][3]. Pseudogenes like RNA5SP464 represent genomic DNA sequences similar to a functional gene (in this case, 5S rRNA), but are typically non-functional due to sequence mutations, truncations, or lack of regulatory elements needed for active expression[2]. Most 5S ribosomal RNA pseudogenes do not produce functional RNA or protein products. However, pseudogenes in general can, in rare cases, affect gene regulation or disease processes through mechanisms such as acting as competitive endogenous RNAs (ceRNAs) or producing regulatory non-coding RNAs[2]. There is currently no evidence that RNA5SP464 itself has functional, disease-related, or therapeutic significance. RNA, 5S ribosomal pseudogene 464 is not a functional gene or a recognized drug target; it is a genomic remnant related to the 5S rRNA gene, lacking evidence for relevant biological activity or disease involvement[1][2][3].

Other names

RN5S464RNA5SP464RNA, 5S ribosomal 464