5S ribosomal RNA pseudogene 475 (RNA5SP475)

5S ribosomal RNA pseudogene 475 (RNA5SP475) is a processed pseudogene that is homologous to the functional 5S ribosomal RNA gene but contains sequence changes or truncations that make it nonfunctional[2][4]. Processed pseudogenes typically arise from the reverse transcription of an RNA molecule and its subsequent insertion back into the genome without the regulatory elements or coding capacity needed for biological activity[2][4]. 5S rRNA itself is a highly conserved structural and functional component of the large ribosomal subunit in eukaryotes, but the pseudogene variant does not contribute to ribosome structure or function[1][3]. Pseudogenes like RNA5SP475 may be detected through genomic sequencing and are typically classified as non-coding elements with no current evidence supporting therapeutic or diagnostic relevance[2][4].

Other names

RN5S475RNA, 5S ribosomal pseudogene 475RNA, 5S ribosomal 475