Target intelligence / Profile preview

5S ribosomal RNA pseudogene 90 (RNA5SP90)

Target
RNA5SP90
Molecular classification
Pseudogene, rRNA pseudogene, Non-coding RNA pseudogene
01

Overview

5S ribosomal RNA pseudogene 90 is a non-functional genomic sequence related to the 5S ribosomal RNA gene. Pseudogenes of ribosomal RNA are frequent in eukaryotic genomes and are the result either of gene duplication followed by mutation (unprocessed pseudogene), gene retrotransposition (processed pseudogene), or gene inactivation (unitary pseudogene)[2][6]. Unlike their parent genes, pseudogenes do not transcribe functional RNAs capable of assembling into ribosomes and contributing to cellular protein synthesis[2]. Most rRNA pseudogenes, including RNA5SP90, are not therapeutic targets, and there is no evidence that this particular pseudogene encodes a molecule with biological or disease roles. In terms of molecular classification, it falls into the category of "rRNA pseudogene" within "non-coding RNA pseudogenes"[6]. While some pseudogenes have been implicated in cancer-related regulatory activities, this is specific to certain families and loci, not universally applicable to all, and there is no evidence for such a role for RNA5SP90[4]. Summary of key points: - RNA5SP90 is a pseudogene, not a protein, not a receptor, enzyme, or transporter, and not considered a therapeutic target. - Aliases are variants of its full name, none linked to a therapeutic context. - Molecular family: pseudogenes (specifically rRNA pseudogene)[6]. - No known drugs, biomarkers, or safety issues. - No established biological or disease involvement for this pseudogene. - Entry is technically incorrect for drug/receptor target databases (not a valid target).

Other names
RN5S90RNA, 5S ribosomal 90RNA5SP90
02

Mechanism of action

None known

03

Biological functions

None established for pseudogenes generallyParent gene involved in ribosome structure and function, but this pseudogene does not encode active RNA
04

Disease associations

No direct role in disease established for this specific pseudogeneExpression of some pseudogenes can be linked to cancer risk and prognosis, but not demonstrated for RNA5SP90 specifically

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