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The 60S ribosomal protein L36 pseudogene, annotated by Ensembl as ENSG00000253383, is a non-coding segment of genomic DNA sharing high sequence similarity with the protein-coding RPL36 gene. It represents one of the multiple processed pseudogenes for ribosomal protein L36 found throughout the human genome. Pseudogenes do not encode functional proteins and are generally considered biologically inactive, lacking both the protein product and direct involvement in cellular or disease pathways. As with many ribosomal protein genes, pseudogenes for RPL36 are widely dispersed and serve primarily as genomic relics without a recognized function in health or disease[1][3][6]. Key clarification: - ENSG00000253383 refers to a *pseudogene* and not the functional ribosomal protein L36 itself. If information about the *active* ribosomal protein is needed, the protein-coding gene RPL36 (ENSG00000130255) should be referenced instead[5][7][10]. If your use case demands details about the functional "60S ribosomal protein L36," please specify, as the above strictly describes the pseudogene.
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