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Abhydrolase domain containing 18 (ABHD18)

Target: ABHD18
Molecular classification: Enzyme, Alpha/beta hydrolase superfamily

Overview

Abhydrolase domain containing 18 (ABHD18) is a protein-coding gene encoding a member of the alpha/beta hydrolase superfamily involved in fat metabolism. It is ubiquitously expressed and associated with hepatocellular carcinoma risk based on Alu repeat variation. Other disease associations include microcephaly and ceroid lipofuscinosis. It shows expression across various cancer types.

Other names: C4orf29FLJ21106

Biological functions

Fat metabolismLipid metabolism

Disease associations

Hepatocellular carcinomaMicrocephalyCeroid lipofuscinosisCancer

Biomarkers

Alu repeats (HCC risk assessment)

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