ABO blood group pseudogene

The ABO blood group pseudogene, referenced as ENSG00000270624 and LOC401913, is a presumed nonfunctional DNA sequence related to the functional ABO gene locus. The **functional ABO gene** encodes glycosyltransferases critical for determining the **ABO blood group system**, which is of major importance for blood transfusion and organ transplantation compatibility[3][1][5]. Pseudogenes in the ABO gene family, such as LOC401913, do not encode active enzymes and are not known to have direct biological or therapeutic roles in humans. Although some human glycosyltransferase family pseudogenes may have retained unknown or partial functions at the sequence or even protein level, the ABO pseudogene is not a recognized therapeutic target and is not implicated in disease processes or drug interactions[2]. If additional information about "ABO blood group pseudogene" emerges in future literature, its annotation might be updated. For now, it is best classified as a **human pseudogene** with no confirmed biochemical functionality or disease associations.

Other names

LOC401913ABO pseudogeneENSG00000270624