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Acid-Base Balance Regulation
- Molecular classification
- Physiological Process, Homeostatic Mechanism
01
Overview
Acid-base balance regulation refers to the physiological processes that maintain the pH of body fluids within a narrow range, typically arterial pH between 7.36 and 7.44. This regulation is essential for normal cellular metabolism, enzyme function, and overall homeostasis. It involves buffer systems, the respiratory system (regulating CO₂), and the renal system (excreting/reabsorbing acids and bases). Disorders affecting any of these components can result in acidosis or alkalosis with wide-ranging clinical consequences.
02
Biological functions
pH HomeostasisElectrolyte BalanceWaste RemovalCellular MetabolismEnzyme FunctionRespirationRenal Function
03
Disease associations
AcidosisAlkalosisBone DemineralizationNephrolithiasisMuscle WastingChronic Kidney Disease (CKD)ArrhythmiasSeizuresComa
04
Safety considerations
Over-correction of pHFluid overloadElectrolyte imbalances
05
Biomarkers
Arterial pHBlood CO₂ levelsBicarbonate levelsElectrolyte levels
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