Target intelligence / Profile preview

Acidogenic Intestinal Flora

Molecular classification
Microbiota, Bacteria, Firmicutes, Bacteroidetes, Lactic Acid Bacteria (LAB)
01

Overview

Acidogenic intestinal flora refers to the collection of gut microorganisms, primarily bacteria, that produce organic acids, especially short-chain fatty acids (SCFAs), through the fermentation of dietary fibers and other non-digestible compounds in the colon. These bacteria play a crucial role in maintaining gut health by regulating pH, providing energy to colonocytes, and influencing immune responses. The composition and function of acidogenic flora can be significantly impacted by diet and external interventions, with imbalances linked to various diseases.

Other names
Gut Microbiota (Acid-Producing)SCFA-producing BacteriaIntestinal Acid-Forming BacteriaFermentative Gut Bacteria
02

Mechanism of action

Metabolic activity of gut bacteria leading to SCFA production and other beneficial effects, influenced by diet and external interventions.

03

Biological functions

FermentationSCFA ProductionpH RegulationNutrient AbsorptionVitamin SynthesisBile Acid MetabolismImmune Modulation
04

Disease associations

Inflammatory Bowel Disease (IBD)ObesityInfectionColon CancerDysbiosisMetabolic Disorders
05

Safety considerations

Antibiotic-associated dysbiosisPotential for opportunistic infections with altered gut microbiotaVariability in response to prebiotics and probioticsRisk of adverse effects with FMT
06

Interacting drugs

Antibiotics (affecting gut microbiota composition)

3 more in the full profile.

07

Biomarkers

SCFA levels (acetate, propionate, butyrate)Gut microbiota composition (abundance of specific bacterial species)Fecal pHMarkers of inflammation (e.g., cytokines)

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