Target intelligence / Profile preview

Acids

Molecular classification
Other
01

Overview

The term "Acids" is a broad chemical classification rather than a specific therapeutic molecular target such as a protein, receptor, or enzyme. In a medical and pharmacological context, "Acids" most frequently refers to gastric acid (hydrochloric acid produced by parietal cells), which is the target of neutralization by antacids or inhibition by proton pump inhibitors and H2-receptor antagonists to treat conditions like GERD and peptic ulcers (StatPearls, 2023). Other biologically significant acids include bile acids, which are involved in lipid digestion and targeted by sequestrants to lower cholesterol, and fatty acids, which serve as metabolic substrates and signaling molecules (PubMed, 2022). Because the term encompasses vastly different biological entities—ranging from hydrochloric acid in the stomach to DNA (nucleic acid) and amino acids—it lacks the specificity required for a canonical drug target. Consequently, it is classified here as an incorrect or overly broad target name that requires further specification to a particular molecular entity or physiological system.

Other names
Gastric acidBile acidsFatty acidsAmino acidsNucleic acids
02

Mechanism of action

Neutralization of gastric acid; sequestration of bile acids; supplementation of essential fatty or amino acids.

03

Biological functions

MetabolismDigestionCell signalingpH regulation
04

Disease associations

Gastroesophageal reflux diseaseMetabolic disordersInflammationAcidosis
05

Safety considerations

Electrolyte imbalanceAcid-base disturbancesMetabolic alkalosis
06

Interacting drugs

Aluminum hydroxide

4 more in the full profile.

07

Biomarkers

Gastric pHSerum bicarbonateBlood gas analysis (pH)

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