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ACOXL antisense RNA 1 (ACOXL-AS1) is a long non-coding RNA gene found on human chromosome 2q13, transcribed in the antisense direction relative to the coding gene Acyl-CoA oxidase-like (ACOXL)[1][4][7][9]. As a member of the lncRNA family, ACOXL-AS1 likely participates in the regulation of gene expression through mechanisms common to natural antisense transcripts, such as influencing the expression of nearby protein-coding genes via chromatin remodeling, transcriptional interference, or RNA-RNA interactions[2]. The specific biological roles, disease associations, and therapeutic relevance of ACOXL-AS1 remain largely uncharacterized in the scientific literature to date[1][4][9].
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